Making small intestine endoscopy faster with a pill-sized high-tech camera
Greater resolution, sharper images, and more efficient diagnostic processes – this is the promise of an endoscopy capsule developed by Fraunhofer IZM to allow more detailed small intestine diagnostics.
Capsule for small intestine endoscopy – developed in the Endotrace project.
© Fraunhofer IZM | Volker Mai
2001 the first endoscopic capsule took its journey through the small intestine of a human patient. With its miniature camera, the capsule captured thousands of images of the small bowel. six meters of winding intestine had long prevented normal endoscopic diagnostics in this region of the digestive system. Since this breakthrough, capsule endoscopy has become the norm, made possible with a range of different capsule designs.
Traditional capsule endoscopy, however, suffers from one key limitation: Images are captured on a strictly timed sequence, whether the capsule has moved or not. This can create a glut of redundant images that needs to be sifted and filtered by hand. With image capture responding to actual movement, the amount of redundant data can be minimized, with up to a third fewer images to sort through.
The Endotrace research project has now developed a novel endoscopic capsule technology that promises to avoid redundant data. Supported with €1.2 million in funding from the German Ministry of Education and Research, the project was brought to a successful conclusion in November 2018, with the Fraunhofer Institute for Reliability and Microintegration IZM, Ocesco Endoscopy AG, and AMS presenting the fruits of their labor: a ‘treat-sized’ capsule whose unassuming exterior hides cutting-edge technology on the inside. With no fewer than five cameras, a tracer, and a memory module on board, the tiny capsule still has room for its battery pack and an LED light.
How does it know when and where to capture an image? The built-in controller responds to minute changes in the villi that line the intestinal walls and triggers the camera after the capsule has moved a tenth of an inch. Instead of several thousand repetitive images, the Endotrace capsule produces less than half, but far more meaningful data and helps speed up the diagnostic process. This promises a faster reaction to acute conditions like gastrointestinal bleeding. However, it will still take some time before the first capsule will go on its journey through an actual patient’s digestive system: While the technology is ready, the system still has to go through the long medical approval process.
Manuel Seckel, Project Leader at Fraunhofer IZM, explains: “Endotrace is a passion project for me! Endoscopic diagnostics helps save lives – and we are making it that little bit easier and better.”
Other news from the department science
![[Fe]-hydrogenase catalysis visualized using para-hydrogen-enhanced nuclear magnetic resonance spectroscopy](https://img.chemie.de/Portal/News/675fd46b9b54f_sBuG8s4sS.png?tr=w-712,h-534,cm-extract,x-0,y-16:n-xl)
Get the analytics and lab tech industry in your inbox
From now on, don't miss a thing: Our newsletter for analytics and lab technology brings you up to date every Tuesday. The latest industry news, product highlights and innovations - compact and easy to understand in your inbox. Researched by us so you don't have to.
Most read news
More news from our other portals
See the theme worlds for related content
Topic world Diagnostics
Diagnostics is at the heart of modern medicine and forms a crucial interface between research and patient care in the biotech and pharmaceutical industries. It not only enables early detection and monitoring of disease, but also plays a central role in individualized medicine by enabling targeted therapies based on an individual's genetic and molecular signature.
Topic world Diagnostics
Diagnostics is at the heart of modern medicine and forms a crucial interface between research and patient care in the biotech and pharmaceutical industries. It not only enables early detection and monitoring of disease, but also plays a central role in individualized medicine by enabling targeted therapies based on an individual's genetic and molecular signature.
