Agilent Technologies introduces industry's first HPLC-chip/MS system for proteomics
Many biomedical researchers employ proteomics, the systematic analysis of protein expression, structure and function, to study the underlying causes of diseases such as cancer. Traditional techniques used to prepare protein samples for MS analysis, such as nanoflow LC, require complex arrangements of equipment in order to improve separation power, and consume relatively large quantities of sample. Agilent's innovative new system simplifies LC/MS, heightens separation power and sensitivity, and reduces required sample sizes by integrating multiple functionalities on a single microfluidics-based chip.
Agilent's Protein ID HPLC-Chip (G4240A) offers greater peptide coverage and higher protein identification compared with nanoflow LC/MS. Smaller than a credit card, the company's unique HPLC-Chip for protein identification seamlessly integrates sample enrichment and separation capability of a nanoflow LC system with the intricate connections and spray tips used in electrospray mass spectrometry. The technology eliminates 50 percent of the fittings and connections typically required in an LC/MS system, dramatically reducing the possibility of leaks and dead volumes, significantly simplifying workflow, and increasing sensitivity and reliability during analysis.
To enable compliance and experiment management, the HPLC-Chip includes a radio frequency tag that contains information such as chip ID and type, documentation, diagnostic and operational data, and additional memory for user comments.
Most read news
Topics
Organizations
Other news from the department research and development
Get the analytics and lab tech industry in your inbox
From now on, don't miss a thing: Our newsletter for analytics and lab technology brings you up to date every Tuesday. The latest industry news, product highlights and innovations - compact and easy to understand in your inbox. Researched by us so you don't have to.
More news from our other portals
See the theme worlds for related content
Topic World Mass Spectrometry
Mass spectrometry enables us to detect and identify molecules and reveal their structure. Whether in chemistry, biochemistry or forensics - mass spectrometry opens up unexpected insights into the composition of our world. Immerse yourself in the fascinating world of mass spectrometry!
Topic World Mass Spectrometry
Mass spectrometry enables us to detect and identify molecules and reveal their structure. Whether in chemistry, biochemistry or forensics - mass spectrometry opens up unexpected insights into the composition of our world. Immerse yourself in the fascinating world of mass spectrometry!
Topic World Chromatography
Chromatography enables us to separate, identify and thus understand complex substances. Whether in the food industry, pharmaceutical research or environmental analysis - chromatography opens up a treasure trove of information about the composition and quality of our samples. Discover the fascinating world of chromatography!
Topic World Chromatography
Chromatography enables us to separate, identify and thus understand complex substances. Whether in the food industry, pharmaceutical research or environmental analysis - chromatography opens up a treasure trove of information about the composition and quality of our samples. Discover the fascinating world of chromatography!