New regulatory protein of the neuronal cytoskeleton identified

28-Apr-2025 - The growth and function of nerve cells is based on a lattice-like structure called membrane-associated periodic skeleton (MPS). However, how the organization of the MPS is controlled has not been elucidated until now. A team from the Max Planck Institutes for Medical Research and for ...

How DNA Self-Organizes in the Early Embryo

25-Apr-2025 - An international research team led by Helmholtz Munich has, for the first time, provided a detailed insight into how the spatial organization of genetic material is established in the cell nucleus of early embryos within the first hours after fertilization. Surprisingly, embryos demonstrate a ...

New imaging reveals the secrets of cellular traffic control

Texas A&M University researchers work with experts from EMBL Imaging Centre to uncover how molecules navigate the nuclear pore complex

25-Mar-2025 - Just as cities must carefully manage the flow of cars in and out of downtown, cells regulate the movement of molecules in and out of the nucleus. This microscopic metropolis relies on intricate gateways – nuclear pore complexes (NPCs) – within the nuclear envelope – to control its molecular ...

Science on the back burner: European laboratories struggle with massive restrictions

Great sustainability ambitions and willingness to innovate despite the need to save money

10-Mar-2025 - The life science industry is at a critical turning point: celebrated as systemically relevant during the coronavirus pandemic, many laboratories are now struggling with massive restrictions. A recent Europe-wide survey by laboratory equipment supplier Starlab of 378 laboratory employees from five ...

A method to purify proteins with light

Gentler and more efficient than previous procedures

06-Mar-2025 - Proteins play a key role in the life sciences — from basic research and biotechnological applications to the development and manufacturing of pharmaceuticals. Scientists at the Technical University of Munich (TUM) have developed a method that relies on physics rather than conventional chemistry ...

Refining the CRISPR scissors

Research team unveils novel anti-CRISPR protein mechanism for precise control of genome editing technologies

20-Feb-2025 - The CRISPR-Cas gene scissors offer a wide range of potential applications, from the treatment of genetic diseases to antiviral therapies and diagnostics. However, to safely harness their powers, scientists are searching for mechanisms that can regulate or inhibit the systems’ activity. Enter the ...

Revvity Announces Financial Results for the Fourth Quarter and Full Year of 2024

"We finished last year on a strong note positioning us well as we head into 2025"

04-Feb-2025 - Revvity, Inc. reported financial results for the fourth quarter and full year ended December 29, 2024. Fourth Quarter 2024 The Company reported GAAP earnings per share of $0.78, as compared to $0.64 in the same period a year ago. GAAP revenue for the quarter was $729 million, as compared to $696 ...

Developing a CRISPR therapy for muscular dystrophy

09-Jan-2025 - Researchers at the Experimental and Clinical Research Center in Berlin are developing a targeted treatment for muscular dystrophy with the help of gene-editing. Preclinical research led by the Spuler Lab published in “Nature Communications” now paves the way for first-in-human clinical ...

Michael Grosse to succeed Joachim Kreuzburg as Chief Executive Officer of Sartorius AG

Grosse to take over as Group CEO on July 1, 2025

18-Dec-2024 - The Supervisory Board of Sartorius AG appointed Dr. Michael Grosse Chief Executive Officer of Sartorius. He will take over this position on July 1, 2025, from Dr. Joachim Kreuzburg, who will continue to lead the company until that time. The appointment is the result of a selection process that ...

CRISPR-Cas technology: ETH researchers have uncovered a serious side effect

A molecule designed to make the process more efficient destroys parts of the genome

05-Dec-2024 - Genome editing with various CRISPR-Cas molecule complexes has progressed rapidly in recent years. Hundreds of labs around the world are now working to put these tools to clinical use and are continuously advancing them. CRISPR-Cas tools allow researchers to modify individual building blocks of ...