AI-driven breakthroughs in cells study: advancements in super-resolution microscopy

By integrating AI with super-resolution microscopy, cellular biology is advancing in new and exciting ways

12-Dec-2023 - In 2014, the Nobel Prize in Chemistry celebrated the breakthroughs in super-resolution microscopy, a technology that allows us to capture highly detailed images of small parts of cells using fluorescent microscopy. Despite its success, the resolution of super-resolution microscopy still can’t ...

Researchers from Poland, France and Italy are honored for their work in cell biology, biomineralization and photonics

WITec Paper Award 2023 Recognizes Outstanding Publications

31-Jul-2023 - The WITec Paper Awards 2023 have been presented to scientists from Poland, France and Italy for their work in cell biology, biomineralization and the development of photonic devices, respectively. The competition recognizes three scientific publications per year that contain results acquired with ...

Research team shows how a cell’s form can be reversed

Light-switchable molecules in membranes enable different forms of living cells to be studied

28-Jun-2023 - A research team led by Prof. Bart Jan Ravoo (University of Münster) and Prof. Timo Betz (University of Göttingen) describes for the first time how living cells can be reversibly deformed by specifically influencing the cell membrane using light. Membranes fulfil a variety of tasks in living ...

Seeing inside cells with an integrated nanowire probe

Real-time, in-situ sensing and tracking of cell development and maturation is achieved using a label-free nano-optical device

20-Jan-2022 - The biological intracellular microenvironment is complex, made up of various cell compartments and intracellular substances. To fully characterize the physiological function of living cells, one of the key factors is the development of micro/nanoprobes for subcellular measurement. Current ...

World record broken for thinnest X-ray detector ever created

Highly sensitive and with a rapid response time, the new X-ray detector is less than 10 nanometres thick and could one day lead to real-time imaging of cellular biology

10-Nov-2021 - Scientists in Australia have used tin mono-sulfide (SnS) nanosheets to create the thinnest X-ray detector ever made, potentially enabling real-time imaging of cellular biology. X-ray detectors are tools that allow energy transported by radiation to be recognised visually or electronically, like ...

AI helping to quantify enzyme activity

22-Oct-2021 - Without enzymes, an organism would not be able to survive. It is these biocatalysts that facilitate a whole range of chemical reactions, producing the building blocks of the cells. Enzymes are also used widely in biotechnology and in our households, where they are used in detergents, for ...

Dissecting protein assemblies

New molecular details from mitochondria

14-Aug-2020 - Super-resolution MINFLUX nanoscopy, developed by Nobel laureate Stefan Hell and his team, is able to discern fluorescent molecules that are only a few nanometers apart. In an initial application of this technique to cell biology, researchers led by Stefan Hell and Stefan Jakobs have now optically ...

High-end Microscopy Refined

New details are known about an important cell structure

06-Jul-2020 - For the first time, two Würzburg research groups have been able to map the synaptonemal complex three-dimensionally with a resolution of 20 to 30 nanometres. The synaptonemal complex is a ladder-like cell structure that plays a major role in the development of egg and sperm cells in humans and ...

Shaping light lets 2D microscopes capture 4D data

Invention adds new dimension to fluorescent microscopy

20-Feb-2019 - Rice University researchers have added a new dimension to their breakthrough technique that expands the capabilities of standard laboratory microscopes. Two years ago, the Rice lab of chemist Christy Landes introduced super temporal resolution microscopy, a technique that allowed researchers to ...

Multiplexed Morse signals from cells

01-Apr-2016 - How many sorts, in how many copies? The biochemical processes that take place in cells require specific molecules to congregate and interact in specific locations. A novel type of high-resolution microscopy developed at the Max Planck Institute for Biochemistry in Martinsried and Harvard ...