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New imaging reveals the secrets of cellular traffic control

Texas A&M University researchers work with experts from EMBL Imaging Centre to uncover how molecules navigate the nuclear pore complex

25-Mar-2025 - Just as cities must carefully manage the flow of cars in and out of downtown, cells regulate the movement of molecules in and out of the nucleus. This microscopic metropolis relies on intricate gateways – nuclear pore complexes (NPCs) – within the nuclear envelope – to control its molecular ...

diseases neurodegenerative diseases cancers

Inflammatory messenger fuels Alzheimer’s

Combination therapy could potentially slow down the deterioration of the brain

20-Mar-2025 - Researchers from Charité – Universitätsmedizin Berlin and the Max Delbrück Center have detailed the precise mechanism through which the inflammatory signaling molecule IL-12 contributes to Alzheimer’s disease. The study was published in the journal Nature Aging.* Microglia, the brain’s immune ...

diseases Alzheimer's disease brain

Schizophrenia manifests itself in the brain structure

The symptoms of schizophrenia vary greatly from person to person

27-Feb-2025 - Schizophrenia is a complex mental illness that affects perception, thinking and feeling. This complexity is reflected in the individual manifestations of the illness: for some patients, the main focus is on perceptual disorders, while for others it is cognitive impairments. "In this sense, there ...

diseases psychiatric diseases brain development

High-Tech Microscopy Enables Tailored Rheumatology Therapies

Applied Precision Medicine

29-Jan-2025 - Researchers at CeMM and the Medical University of Vienna have developed an innovative microscopy-based approach that could predict the best approved drug to treat individual rheumatoid arthritis patients using samples of their blood. Published in the Lancet group journal EBioMedicine, the study ...

diseases autoimmune diseases blood samples

AI in Cell Research: Moscot Reveals Cell Dynamics in Unprecedented Detail

A Turning Point in Medical Research

24-Jan-2025 - Thanks to a new technology called Moscot (“Multi-Omics Single-Cell Optimal Transport”), researchers can now observe millions of cells simultaneously as they develop into a new organ—for example, a pancreas. This groundbreaking method was developed by an international research team led by ...

diseases diabetes artificial intelligence

Decoding HIV’s Tactics

HIRI researchers provide new insights into gene regulation of the virus that causes AIDS

17-Jan-2025 - A team of scientists at the Helmholtz Institute for RNA-based Infection Research (HIRI) in Würzburg and the University of Regensburg has unveiled insights into how HIV-1, the virus responsible for AIDS, skillfully hijacks cellular machinery for its own survival. By dissecting the molecular ...

diseases AIDS HI viruses

Reliable measurement of intrinsically disordered proteins

A new approach allows the shape of a disordered protein to be determined in two different ways - on the same sample

03-Jan-2025 - Proteins are essential for our bodily functions: Thousands of different proteins perform very different tasks. While some form components of our body cells, others act as enzymes to stimulate elementary metabolic processes, serve as hormones or help the immune system in its work in the form of ...

diseases Alzheimer's disease neurodegenerative diseases

CRISPR-Cas technology: ETH researchers have uncovered a serious side effect

A molecule designed to make the process more efficient destroys parts of the genome

05-Dec-2024 - Genome editing with various CRISPR-Cas molecule complexes has progressed rapidly in recent years. Hundreds of labs around the world are now working to put these tools to clinical use and are continuously advancing them. CRISPR-Cas tools allow researchers to modify individual building blocks of ...

diseases hereditary diseases cancer

Capitainer participates in global AI project for advanced lung diagnostics

New project combines AI and self-sampling

04-Dec-2024 - Capitainer, a Swedish MedTech start-up specializing in self-sampling solutions, plays a key role in the international AIR project (Artificial Intelligence Radiology) aimed at improving the diagnostics and monitoring of lung diseases. Through Capitainer's innovative technology, patients can easily ...

diseases lung diseases artificial intelligence

SARS-CoV-2 Spike Protein Accumulation Linked to Long-Lasting Brain Effects

Researchers have identified a mechanism that may explain the neurological symptoms of Long COVID

03-Dec-2024 - The study shows that the SARS-CoV-2 spike protein remains in the brain’s protective layers, the meninges, and the skull’s bone marrow for up to four years after infection. This persistent presence of the spike protein could trigger chronic inflammation in affected individuals and increase the ...

diseases neurodegenerative diseases brain