Structure of virus that infects bacteria in hot springs is revealed

06-Feb-2019 - Scientists have revealed the structure of a virus infecting bacteria that thrive in 160-degree hot springs in places like Yellowstone National Park in Wyoming. The discovery could lead to better targeted delivery of drugs into cells and new DNA sequencing technology, according to a study by ...

Revolutionary imaging technique uses CRISPR to map DNA mutations

22-Nov-2017 - A team of scientists led by Virginia Commonwealth University physicist Jason Reed, Ph.D., have developed new nanomapping technology that could transform the way disease-causing genetic mutations are diagnosed and discovered. Described in a study this novel approach uses high-speed atomic force ...

'Mysterious' non-protein-coding RNAs play important roles in gene expression

16-Jan-2017 - In cells, DNA is transcribed into RNAs that provide the molecular recipe for cells to make proteins. Most of the genome is transcribed into RNA, but only a small proportion of RNAs are actually from the protein-coding regions of the genome. "Why are the non-coding regions transcribed at all? ...

Pilot study successfully uses DNA sequencing to diagnose brain infections

22-Jun-2016 - In a proof-of-principle study, a team of physicians and bioinformatics experts at Johns Hopkins reports they were able to diagnose or rule out suspected brain infections using so called next-generation genetic sequencing of brain tissue samples. The team says its study demonstrates that using ...

Amino acid fingerprints revealed in new study

08-Apr-2014 - Some three billion base pairs make up the human genome—the floor plan of life. In 2003, the Human Genome Project announced the successful decryption of this code, a tour de force that continues to supply a stream of insights relevant to human health and disease. Nevertheless, the primary actors ...

Scripps research team wins $5.1 million to develop DNA sequencing technology

20-Sep-2010 - Scripps Research Institute Professor Reza Ghadiri, Ph.D., has been awarded a four-year, $5.1 million grant as part of a National Institutes of Health (NIH) initiative to spur the development of the next generation of DNA sequencing technologies, which could enable biomedical researchers and ...

LLNL detection technology identifies bacteria, viruses

New LLNL detection technology identifies bacteria, viruses, other organisms within 24 hours array

07-May-2010 - Law enforcement authorities seeking to detect bioterrorism attacks, doctors diagnosing diseases and regulatory agencies checking product safety may find a new ally in a Lawrence Livermore National Laboratory (LLNL) detection technology. The advance, known as the Lawrence Livermore Microbial ...

New detection technique used in analysis of vaccines

12-Apr-2010 - An analysis of vaccines undertaken by researchers from five institutions has found that seven of the vaccines’ DNA content was pretty much as expected, but surprisingly, one also contained DNA of an apparently benign pig virus. This finding is reported in a paper written by lead author Eric ...

New Array-Based Resequencing Approach Deepens Information Content, Speeds Next-Generation Sequencing

14-Jul-2009 - A group of researchers from the Cold Spring Harbor Laboratory (CSHL) and Agilent Technologies Inc. have developed a technique that complements massively parallel next-generation DNA sequencing, using custom microarrays to focus on genomic regions of high interest. The method, published in Nature ...

Random picks better than complicated process in gene identification

08-May-2009 - Researchers at Purdue University have found a way to save time, money and a little frustration in searches for specific genes that shed light on the biological processes associated with all forms of life. Andrew DeWoody, a professor of genetics, and postdoctoral associate Matthew C. Hale have ...