Utilizing CRISPR for better antibiotics

Drug screening with Mobile-CRISPRi

15-Jan-2019 - A University of Wisconsin-Madison researcher and his collaborators at the University of California, San Francisco have repurposed the gene-editing tool CRISPR to study which genes are targeted by particular antibiotics, providing clues on how to improve existing antibiotics or develop new ...

Faulty immune receptor could be reason why many face HIV complications

10-Jan-2019 - For HIV patients, treatments that control the infection have come a long way. But many still struggle with a host of other disease-related complications such as neurocognitive disorders, cardiovascular issues, diabetes and chronic inflammation. Why these complications occur isn't exactly known, ...

Amgen Invests $66 Million In Oxford Nanopore Technologies

24-Oct-2018 - Amgen and Oxford Nanopore Technologies Ltd. announced Amgen's equity investment of £50 million ($66 million) in Oxford Nanopore, a privately-owned, UK-based company advancing a new generation of portable, real-time genetic sequencing technology. Oxford Nanopore has developed and brought to market ...

Flu virus is protected by mucus when airborne, regardless of humidity

08-Jun-2018 - Mucus and other airway secretions that are expelled when a person with the flu coughs or exhales appear to protect the virus when it becomes airborne, regardless of humidity levels, a creative experiment conducted by the University of Pittsburgh and Virginia Tech discovered. The results refute ...

Discovery of how HIV hedges its bets opens the door to new therapies

14-May-2018 - A stem cell is one with infinite possibilities. So, for decades, scientists have puzzled over how the cell chooses to keep being a stem cell and continue dividing, or specialize into a specific cell type, like a heart or brain cell. The same type of decision is made by HIV. When the virus infects ...

Revolutionary imaging technique uses CRISPR to map DNA mutations

22-Nov-2017 - A team of scientists led by Virginia Commonwealth University physicist Jason Reed, Ph.D., have developed new nanomapping technology that could transform the way disease-causing genetic mutations are diagnosed and discovered. Described in a study this novel approach uses high-speed atomic force ...

Tiny fibers open new windows into the brain

Three-in-one design allows genetic, chemical, optical, and electrical inputs and outputs.

24-Feb-2017 - For the first time ever, a single flexible fiber no bigger than a human hair has successfully delivered a combination of optical, electrical, and chemical signals back and forth into the brain, putting into practice an idea first proposed two years ago. With some tweaking to further improve its ...

'Mysterious' non-protein-coding RNAs play important roles in gene expression

16-Jan-2017 - In cells, DNA is transcribed into RNAs that provide the molecular recipe for cells to make proteins. Most of the genome is transcribed into RNA, but only a small proportion of RNAs are actually from the protein-coding regions of the genome. "Why are the non-coding regions transcribed at all? ...

Study outlines framework for identifying disease risk in genome sequence

13-Jan-2017 - Imagine a day when you visit the doctor's office for your annual physical. Your physician orders routine tests - cholesterol, glucose and blood count - but they also order a sequence of your genome, all 3 billion letters of it. Routine genomic testing is not far away, according to researchers at ...

OGT opens New York office and appoints US sales team

22-Nov-2012 - Oxford Gene Technology (OGT) announced that it has opened a new office in Tarrytown, New York to support and grow its cytogenetics arrays and next generation sequencing business in the US.The new office will enable OGT to provide hands-on technical support and training to its existing US ...