Genome analysis - 7 News from the science department by Max-Planck-Gesellschaft

Genome analysis - 7 News from the science department by Max-Planck-Gesellschaft

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New tool maps microbial diversity with unprecedented details

The innovative tool allows the analysis of structural genomic variations in microbial populations

26-Jun-2024 - Researchers from the Max Planck Institute for Biology Tübingen developed the groundbreaking tool SynTracker. SynTracker expands traditional microbial analysis by considering genomic structural variation to complement existing SNP-based methods. This innovation reveals more precision and depths of ...

genome analysis evolution microbes
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Beethoven’s genome: New study reveals hereditary diseases and a family mystery

Scientists have sequenced the composer’s genome using five genetically matching hair locks

24-Mar-2023 - The study shows Beethoven was predisposed to liver disease, and infected with Hepatitis B, which – combined with his alcohol consumption – may have contributed to his death. Furthermore, DNA from modern relatives points to an extramarital ‘event’ in Beethoven’s paternal line. Johannes Krause, ...

genome analysis alcohol consumption deafness
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The architecture of shattered genomes

Hunting for disease clues in the dark matter of our DNA

20-Jan-2023 - Scientists have reconstructed the chromosomes of patients with an extremely high number of aberrations in their genome that could alter the expression of nearby genes and potentially cause disease. Their results were published in Nature Communications in October 2022. “We are only beginning to ...

genome analysis chromosomes chromothripsis
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Speeding up sequence alignment across the tree of life

A sequence search engine for a new era of conservation genomics

09-Apr-2021 - A team of researchers from the Max Planck Institutes of Developmental Biology in Tübingen and the Max Planck Computing and Data Facility in Garching develops new search capabilities that will allow to compare the biochemical makeup of different species from across the tree of life. Its ...

genome analysis databases genomes
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New tool helps to ‘spot the difference’ in genome organisation

This enables scientists to track down causes of diseases more quickly

22-Oct-2020 - The way DNA is organized in the cell nucleus is very important for the normal development and function of the cell. A mutation that affects the packaging of the genetic material in the cell nucleus can lead to developmental disorders or diseases such as cancer. A team of scientists from the Max ...

genome analysis cancer cell nucleus
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The genetic basis of bats’ superpowers revealed

First six reference-quality bat genomes released and analysed

24-Jul-2020 - For the first time, the raw genetic material that codes for bats’ unique adaptations and superpowers such as the ability to fly, to use sound to move effortlessly in complete darkness, to survive and tolerate deadly diseases, to resist ageing and cancer - has been fully revealed. Bat1K, a global ...

genome analysis bats genome sequencing
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Neandertal genome project reaches its goal

High-quality Neandertal genome provides novel insights into human origins

20-Dec-2013 - An international research team led by Kay Prüfer and Svante Pääbo of the Max Planck Institute for Evolutionary Anthropology in Leipzig, Germany, has determined a high-quality genome sequence of a Neandertal woman. The genome allows detailed insights into the relationships and population history ...

genome analysis Denisovan genome DNA sequencing
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