Pathogen identification — next-generation sequencing optimizes diagnostics

Novel method takes inspiration from law enforcement

17-Jun-2024 - Invasive infections such as sepsis require immediate and targeted treatment. Experts from the Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB and group partners have succeeded in establishing a reconceptualized detection principle that can make a crucial contribution to ...

Complex green organisms emerged a billion years ago

Research team investigates the emergence of multicellularity

25-Jan-2024 - Of all the organisms that photosynthesize, land plants have the most complex bodies. How did this morphology emerge? A team of scientists led by the University of Göttingen has taken a deep dive into the evolutionary history of morphological complexity in streptophytes, which include land plants ...

PathoFact identifies pathogens faster and more accurately

New open access tool for the diagnosis of infections

03-Mar-2021 - Scientists from the Luxembourg Centre for Systems Biomedicine (LCSB) and the Department of Life Sciences and Medicine of the University of Luxembourg have developed a new bioinformatics tool that can help them identify pathogens much faster and more accurately than was ever possible with ...

Dissecting bacterial infections at the single-cell level

22-Nov-2016 - Technological advances are making the analysis of single bacterial infected human cells feasible, Würzburg researchers have used this technology to provide new insight into the Salmonella infection process. Infectious diseases are a leading cause of mortality worldwide. The development of novel ...

Columbia researchers report novel approach for single molecule electronic DNA sequencing

Columbia researchers have developed a novel approach to potentially sequence DNA in nanopores electronically at single molecule level with single-base resolution

25-Sep-2012 - DNA sequencing is the driving force behind key discoveries in medicine and biology. For instance, the complete sequence of an individual's genome provides important markers and guidelines for medical diagnostics and healthcare. Up to now, the major roadblock has been the cost and speed of ...

Genomic sequence and comparison of 2 macaques reveal new insights into biomedical research

19-Oct-2011 - The South China Center for Innovative Pharmaceuticals, Sun Yat-Sen University, and BGI, the world's largest genomic organization, announced that they were among the research organizations from China, US and UK comprising an international research group that completed the genome sequence and ...

CLC bio achieves massive growth in 2009 and closes year with 7-figure deal

08-Jan-2010 - CLC bio announced that their financial year 2009 was closed with a 7-figure US Dollar deal involving a multinational corporation working extensively with high-throughput sequencing data analysis on multiple levels. Vice President of Global Sales & Marketing at CLC bio, Jan Lomholdt, states, "I ...

CLC bio part of EU project aiming to diagnose genetic disorders using high-throughput sequencing

10-Dec-2009 - Tthe EU project, TECHGENE, that focuses on developing Next Generation Sequencing (NGS) diagnostic tools for genetic disorders, announced that CLC bio has been selected as the software partner for this project. The goal of the TECHGENE project is to incorporate the novel massively parallel ...

CSHL scientists harness logic of 'Sudoku' math puzzle to vastly enhance genome-sequencing capability

'DNA Sudoku' pools multitude of DNA samples for sequencing in manner analogous to solving a Sudoku grid

30-Jun-2009 - A math-based game that has taken the world by storm with its ability to delight and puzzle may now be poised to revolutionize the fast-changing world of genome sequencing and the field of medical genetics, suggests a new report by a team of scientists at Cold Spring Harbor Laboratory (CSHL). The ...

Genomatix gets Patent for Comparative Genomics Method

Identification and assignment of functionally corresponding regulatory sequences throughout different eukaryotic genomes

16-Mar-2009 - Genomatix Software announced that it was issued patent No. EP 1 800 232 B1, “Identification and assignment of functionally corresponding regulatory sequences for orthologous loci in eukaryotic genomes” by the European Patent Office. The Patent relates to a method for identification of networks ...