Microscopy - 27 News from the science department by Max-Planck-Gesellschaft for the lab analysis / lab measurement technology industry

Microscopy - 27 News from the science department by Max-Planck-Gesellschaft for the lab analysis / lab measurement technology industry

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10,000 times faster than traditional methods

New computational framework discovers experimental designs in microscopy

12-Dec-2024 - For human researchers, it takes many years of work to discover new super-resolution microscopy techniques. The number of possible optical configurations of a microscope — for example, where to place mirrors or lenses — is enormous. Researchers at the Max Planck Institute for the Science of Light ...

microscopy artificial intelligence optical microscopy
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Researchers can measure distances in molecules optically

MINFLUX microscopy allows the determination of distances within biomolecules using an optical microscope

15-Oct-2024 - A team led by physicists Steffen Sahl and Stefan Hell at the Max Planck Institute for Multidisciplinary Sciences in Göttingen and the Max Planck Institute for Medical Research in Heidelberg has succeeded in measuring distances within biomolecules using a light microscope, down to one nanometer ...

microscopy biomolecule analysis biomolecules
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Discovery of the first fractal molecule in nature

‘We stumbled on this structure completely by accident and almost couldn’t believe what we saw when we first took images of it using an electron microscope’

12-Apr-2024 - Snowflakes, fern leaves, romanesco cauliflower heads: many structures in nature have a certain regularity. Their individual parts resemble the shape of the whole structure. Such shapes, which repeat from the largest to the smallest, are called fractals. But regular fractals that match almost ...

microscopy biomolecules cyanobacteria
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Identify, engage, assassinate: How seahorse-like toxins kill insects

Researchers reveal the first-ever detailed structure of the bacterial toxin Mcf1: Useful for engineering novel biopesticides

02-Feb-2024 - Insect-killing bacteria typically release toxins to slay their hosts. The bacterium Photorhabdus luminescens, for example, pumps insect larvae full of the lethal ‘Makes caterpillars floppy 1’ (Mcf1) toxin, leading them to first become droopy and then dead. However, it has so far been a mystery ...

microscopy bacterial toxins biopesticides
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“Optical fingerprints” on an electron beam

Researchers observe non-linear optical processes in the electron microscope

17-Jan-2024 - The precise control of electron beams in so-called transmission electron microscopes (TEM) makes it possible to analyze materials or molecules at the atomic level. Combined with short light pulses, these devices can also be used to analyze dynamic processes. Researchers from Göttingen and ...

microscopy electron microscopy electrons
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Tailored electron pulses for improved electron microscopy

Interplay of free electrons

16-Oct-2023 - Electron microscopes provide unique vistas of nanoscale structures, but their resolution is limited by the mutual repulsion of electrons. Researchers in Göttingen have now succeeded in precisely measuring the influence of these interactions. They discovered an “energetic fingerprint” in which the ...

microscopy electron microscopes electron microscopy
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Ångström-Resolution Fluorescence Microscopy

This innovation is poised to usher in a paradigm shift in our approach to study biological systems with thus far unprecedented detail

05-Jun-2023 - A breakthrough in fluorescence microscopy has been achieved by the research group of Ralf Jungmann at the Max Planck Institute of Biochemistry (MPIB) and Ludwig-Maximilians-Universität (LMU) Munich. The team developed Resolution Enhancement by Sequential Imaging (RESI), a revolutionary technique ...

microscopy fluorescence microscopy super resolution microscopes
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A further advance in super-resolution fluorescence microscopy

Fast even at the nanometer level

14-Mar-2023 - Scientists led by Nobel Laureate Stefan Hell at the Max Planck Institute for Medical Research in Heidelberg have developed a super-resolution microscope with a spatio-temporal precision of one nanometer per millisecond. An improved version of their recently introduced MINFLUX super-resolution ...

microscopy protein analysis proteins
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Quantum simulator enables first microscopic observation of charge carriers pairing

Research results could be key to understanding high-temperature superconductors

23-Jan-2023 - A team of researchers at the MPQ has for the first time monitored in an experiment how holes (positive charge carriers) in a solid-state model combined to form pairs. This process could play an important role in understanding high-temperature superconductivity. Using a quantum simulator, ...

microscopy high temperature superconductivity high-temperature superconductors
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With light into the nanoworld: How optical microscopes allow detailed investigations of nanoparticles

The goal: the development of novel nanoparticles for biomedical applications.

21-Dec-2022 - It sounds like trying to scan a vinyl record with a hammer: Light is actually too "coarse" to image small particles on the nanometer scale. However, in their project "Supercol"- funded by the European Union - scientists want to achieve just that: The investigation of nanoparticles with light. To ...

microscopy biomedicine fluorophores
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