Novel label-free biosensor platform for innovate modern drug screening

lino Biotech closes seed financing round

19-Nov-2020 - Switzerland

After almost a decade of initial invention and joint research on the Focal molography technology at Roche, a leading player in the diagnostics and pharmaceutical area, and ETH Zurich as one of Europe’s most renowned research institutes, lino Biotech AG has licensed the technology to further develop and commercialize Focal Molography. The company has received 7-digit financing from lead-investors HTGF, Roche Ventures and several family offices.

pixabay.com

Symbolic image

This broadly patented technology offers label-free detection assays using the power of molecular diffraction while eliminating disturbances of environmental factors such as changes in temperature or non-specific binding. lino’s biosensor platform offers industry customers and researchers a unique way to study molecular interactions in living cells and crude biosystems. Importantly, its broad application spectrum can for the first time, measure drug binding to transmembrane proteins while simultaneously observe intracellular signaling. Additional applications can be found in bioprocessing.

With access to modern clean room facilities, the company currently offers its services to selected industry partners as contract research service.

"Experiments with pharma partners have highlighted the value of Focal Molography. However, we are still at the beginning to understand the value of Molography for different industries. For example, we currently evaluate the potential of monitoring multiple parameters in bioreactors as well as another pharma case of measuring high-affinity drug-target interactions in real-time over several days. Two very different applications for different customers that both seem feasible with the technology at hands", said Dr. Mirko Stange, CEO of lino Biotech.

"Molography offers the chance to combine several assays into one single measurement of living cells, thus delivering distinguish information on target specific interactions and shorting development times for novel drugs", said Dr. Martin Pfister, Principal at HTGF.

Other news from the department business & finance

These products might interest you

Octet R2 / Octet R4 / Octet R8

Octet R2 / Octet R4 / Octet R8 by Sartorius

Full power on 2, 4 or 8 channels: Label-free and GxP-compliant analysis of molecular interactions

Innovative label-free real-time protein quantification, binding kinetics and rapid screenings

protein analyzers
Octet SF3

Octet SF3 by Sartorius

Surface Plasmon Resonance (SPR) using Single Dynamic Injections for Kinetics and Affinities

Curvature is Key - Adding a ‘Third Dimension’ to the Binding Curve

Octet RH16 and RH96

Octet RH16 and RH96 by Sartorius

Efficient protein analysis for process optimisation and manufacturing control in high-throughput

Label-free protein quantification and characterization of protein-protein interactions

protein analyzers
Loading...

Most read news

More news from our other portals

Under the magnifying glass: The world of microscopy

Something is happening in the life science industry ...

This is what true pioneering spirit looks like: Plenty of innovative start-ups are bringing fresh ideas, lifeblood and entrepreneurial spirit to change tomorrow's world for the better. Immerse yourself in the world of these young companies and take the opportunity to get in touch with the founders.

See the theme worlds for related content

Topic World Cell Analysis

Cell analyse advanced method allows us to explore and understand cells in their many facets. From single cell analysis to flow cytometry and imaging technology, cell analysis provides us with valuable insights into the structure, function and interaction of cells. Whether in medicine, biological research or pharmacology, cell analysis is revolutionizing our understanding of disease, development and treatment options.

5+ products
5 brochures
View topic world
Topic World Cell Analysis

Topic World Cell Analysis

Cell analyse advanced method allows us to explore and understand cells in their many facets. From single cell analysis to flow cytometry and imaging technology, cell analysis provides us with valuable insights into the structure, function and interaction of cells. Whether in medicine, biological research or pharmacology, cell analysis is revolutionizing our understanding of disease, development and treatment options.

5+ products
5 brochures