Malvern Instruments establishes new biopharmaceutical applications laboratory in the heart of San Diego’s biotech community

03-Aug-2015 - USA

Malvern Instruments has established a new biopharmaceutical applications laboratory in the heart of San Diego’s biotechnology cluster. The new laboratory will enable customers and Malvern applications specialists alike to experience and use Malvern’s range of specialist biophysical characterization systems in a working biopharmaceutical environment.

The MicroCal PEAQ-ITC is the new-generation isothermal titration calorimeter, which has become an essential technique in drug discovery.

The new applications lab has been developed in partnership with Sevion Therapeutics, a San Diego based biopharmaceutical company that discovers, develops and acquires next-generation biologics. Sevion Therapeutics will host the laboratory for which Malvern will provide analytical instrumentation, training and continuing support. The lab came on stream in May 2015.

“As evidenced by the work of our Bioscience Development Initiative team, Malvern is absolutely committed to providing cutting edge analytical instrumentation that meets the needs of the biopharmaceutical industry,” said Paul Davies, Global Business Manager at Malvern Instruments. “We work very closely with all parts of the pharmaceutical industry but the highly dynamic nature of biopharmaceutical development and the rapid pace of change make it imperative that we have a fully functioning applications laboratory in an environment where there is access to real-world protein formulations and where our instruments sit within the workflow of a commercial enterprise. I am absolutely delighted that Sevion Therapeutics is our partner in this venture.”

Under the terms of the agreement, several different Malvern analyzers will be installed in the applications laboratory. Initially this will include two microcalorimeters, a multi-detector size exclusion chromatography system; and a Zetasizer Nano ZSP for the measurement of size, electrophoretic mobility of proteins, zeta potential of nanoparticles and surfaces, and optionally the microrheology of protein and polymer solutions. Further protein characterization technologies from Malvern’s portfolio will be installed at future dates.

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