PamGene Platform Adopted for Kinase Drug R&D Program
Collaboration with Johnson & Johnson Pharmaceutical Research & Development
13-Mar-2006
The evaluation program involved kinase inhibitor characterization on a panel of recombinant kinases. Additionally, a number of reference and J&JPRD proprietary kinase inhibitors were characterized in whole cell-based experiments. Kinase activity was measured by phosphorylation profiles (fingerprints) obtained from the kinetic readout from lysates of compound-treated cells.
Organizations
PamGene International
Janssen Pharmaceutica
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