Faster characterization of organic salts

27-Mar-2018 - UZH researchers have developed a novel method that speeds up the process of determining crystal structures of organic salts and significantly reduces the effort required to do so. As about 40 percent of all active pharmaceutical ingredients are salts, this new crystallographic method is set to ...

Drug or duplicate?

Quantum cascade lasers can reliably detect a substance‘s »fingerprint«

26-Mar-2018 - Imagine holding two different medications in your hands, one being the original, the other one being a counterfeit. Both appear exactly the same. Is there any way for you to distinguish them? The answer is: yes. Our quantum cascade laser (QCL) has the ability to identify substances in a split ...

Measuring molecular interactions

Previously unknown interactions between proteins and small metabolic molecules discovered

02-Feb-2018 - ETH researchers have used a new approach to discover previously unknown interactions between proteins and small metabolic molecules in bacterial cells. The technique can also be used to test the effect of medications. Science now has a new “omics” – an interactomics, which deals with the ...

Adjustment of drug dose for rheumatoid arthritis by diagnostic method

Determination of the therapeutic window of adalimumab

06-Oct-2017 - Collaboration between the Immanuel Klinikum Bernau Herzzentrum Brandenburg, the Rheumazentrum Nord-Brandenburg and BioTeZ demonstrates new ways of treating rheumatoid arthritis. Through the introduction of therapeutic antibodies, the treatment results for rheumatoid arthritis (RA) have been ...

Using insects to test for drug safety

09-Sep-2009 - Insects, such as some moths and fruit flies, react to microbial infection in the same way as mammals and so can be used to test the efficiency of new drugs, thereby reducing the need for animal testing. Dr Kevin Kavanagh from the National University of Ireland – Maynooth, presented his research ...