RNA Therapeutics: Ultrasensitive detection and absolute quantification with Droplet Digital PCR
Bio-Rad Laboratories Ltd.
Transforming Bioanalysis of RNA Therapeutics, from Discovery and Development to Manufacturing QC
Advances in therapeutic RNAs have exploded in recent years. These novel drugs have the potential to make personalized medicine a reality and, at the same time, make the term “undruggable” obsolete. Therapeutic RNAs can be used to provide a sequence-specific modulation of gene expression to cause a desired biological response with a beneficial health outcome. Collectively, RNA therapeutics consist of multiple types of RNAs that include small activating RNAs (saRNA), antisense oligonucleotides (ASO), microRNAs (miRNA), small interfering RNAs (siRNA), and messenger RNAs (mRNA). ddPCR technology has proven to be an invaluable analytical asset and is extensively used at various stages of the RNA development and production process to support the development and production of safe and effective RNA-based therapeutics.
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RNA Therapeutics: Ultrasensitive detection and absolute quantification with Droplet Digital PCR
Transforming Bioanalysis of RNA Therapeutics, from Discovery and Development to Manufacturing QC
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