WildDISCO: Visualizing Whole Bodies in Unprecedented Detail

AI Integration: Predicting Disease Progression Without the Use of Animal Models in Research

12-Jul-2023 - Researchers developed a new method called wildDISCO that uses standard antibodies to map the entire body of an animal using fluorescent markers. This revolutionary technique provides detailed 3D maps of structures, shedding new light on complex biological systems and diseases. WildDISCO has the ...

Deadly virus structures point toward new avenues for vaccine design

By comparing the structures of protein complexes from different lineages of the dangerous Lassa virus, a Scripps Research team identified new antibodies and vaccine targets

12-Jun-2023 - Every year, hundreds of thousands of people in West Africa become infected with Lassa virus, which can cause Lassa fever and lead to severe illness, long-term side effects or death. There are currently no widely approved treatments or vaccines for the disease. Now, scientists at Scripps Research ...

Enhancing at-home COVID tests with glow-in-the dark materials

09-Mar-2023 - Researchers at the University of Houston are using glow-in-the-dark materials to enhance and improve rapid COVID-19 home tests. If you’ve taken an at-home COVID-19 or pregnancy test, then you’ve taken what is scientifically called a lateral flow assay (LFA) test, a diagnostic tool widely used ...

Synthetic Genes for Flu Test

Electrochemical biosensor for antibody detection

17-Jan-2023 - The quantitative detection of specific antibodies in complex samples such as blood can inform on many different diseases but usually requires a complicated laboratory procedure. A new method for the rapid, inexpensive, yet quantitative and specific point-of-care detection of antibodies has now ...

White, red, and blue signals alert you to dangerous germs!

A simple, rapid method to simultaneously identify multiple food poisoning bacteria

01-Sep-2022 - Osaka Metropolitan University scientists have developed a simple, rapid method to simultaneously identify multiple food poisoning bacteria, based on color differences in the scattered light by nanometer-scaled organic metal nanohybrid structures (NHs) that bind via antibodies to those bacteria. ...

Smart contact lenses for cancer diagnostics and screening

15-Aug-2022 - Scientists from the Terasaki Institute for Biomedical Innovation (TIBI) have developed a contact lens that can capture and detect exosomes, nanometer-sized vesicles found in bodily secretions which have the potential for being diagnostic cancer biomarkers. The lens was designed with microchambers ...

New test may predict COVID-19 immunity

Paper test measures the level of neutralizing antibodies in a blood sample and could help people decide what protections they should take against infection

12-Aug-2022 - Most people in the United States have some degree of immune protection against Covid-19, either from vaccination, infection, or a combination of the two. But, just how much protection does any individual person have? MIT researchers have now developed an easy-to-use test that may be able to ...

Corona: New Insights into Antibody Response against Viral Variants

Cross-reactivity could prove to be an important aspect of future vaccinations

27-Jan-2022 - In the journal Science, researchers from Charité – Universitätsmedizin Berlin and Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE) present new findings on the immune response against the coronavirus SARS-CoV-2. Their study is based on investigations of antibodies elicited by infection ...

Highly potent and stable nanobodies stop SARS-CoV-2

Alpacas provide blueprints for mini-antibodies

30-Jul-2021 - A team of researchers has developed mini-antibodies that efficiently eliminate the SARS-CoV-2 coronavirus and its dangerous new variants. The so-called nanobodies bind and neutralize the virus up to 1000 times better than previously developed mini-antibodies. In addition, the researchers were ...

Detecting COVID-19 antibodies in 10-12 seconds

12-Jan-2021 - Researchers at Carnegie Mellon University report findings on an advanced nanomaterial-based biosensing platform that detects, within seconds, antibodies specific to SARS-CoV-2, the virus responsible for the COVID-19 pandemic. In addition to testing, the platform will help to quantify patient ...