New imaging analysis method revolutionizes the diagnosis of head and neck tumors

01-Nov-2024 - Head and neck cancers are among the ten most common cancers worldwide. Head and neck tumors account for about 3-5% of all cancers, with squamous cell carcinomas being the predominant form. They occur in areas such as the oral cavity, pharynx and larynx. An international team of researchers led by ...

Seeing cancer’s spread through a computational window

Computational model allows researchers to simulate cellular-scale interactions across unprecedented distances in the human vasculature

29-Nov-2023 - Biomedical engineers at Duke University have significantly enhanced the capabilities of a computational model that simulates the movement of individual cancer cells across long distances within the entire human body. Called “Adaptive Physics Refinement (APR),” the approach captures detailed ...

How stem cells and immune cells communicate

Lisec Artz Award for Simon Haas: Groundbreaking discovery of an unknown protective mechanism against blood cancer from stem cells

17-Nov-2023 - Blood cancer is often driven by mutations in stem cells, which are key target cells in the search for innovative early-stage therapies. Dr. Simon Haas, head of a lab within the joint research focus of the Berlin Institute of Health at Charité (BIH), Charité – Universitätsmedizin Berlin, and the ...

A protein on cancer cells supports immune response against tumors

Surprising discovery

19-Sep-2023 - Scientists from the German Cancer Research Center (DKFZ) identify a new and surprising function of a membrane protein on the surface of cancer cells: It supports and stabilizes an important "co-stimulatory" factor that enhances the activation of T cells, thus improving the immune response against ...

How can we fight blood cancer more effectively?

Several hundred different treatment combinations to be tested simultaneously outside the body

02-May-2023 - Despite approved treatments being available, multiple myeloma remains incurable. But researchers at ETH Zurich and University Hospital Zurich set out to improve treatment outcomes by testing hundreds of existing therapeutics outside the body to predict their effectiveness. Multiple myeloma is a ...

New Molecular Microscopy Uncovers how Breast Cancer Spreads

"The exciting thing about this technology is that for the first time, we can see how the environment shapes cancer evolution"

11-Nov-2022 - Researchers have created a tool that maps how breast cancer grows in previously unseen detail, and highlights how the cells around the tumour may be the key to controlling the spread of disease. The new technology can trace which populations of breast cancer cells are responsible for the spread ...

Computer tool analyzes in detail genetic alterations in the genome of cancer cells

Developed by CSIC, CiberAMP allows establishing direct correlations between changes in the number of gene copies in tumor cells and their expression levels

18-Oct-2022 - A team of researchers from the Salamanca Cancer Research Center (CIC-CSIC-US), a joint institute of the Spanish National Research Council (CSIC) and the University of Salamanca, has developed a new computer tool, called CiberAMP, to analyze in more detail the genetic alterations in the genome of ...

Model system provides insight into the growth of pancreatic tumors

Researchers develop innovative organoid model to study pancreatic cancer

07-Oct-2022 - Researchers at the Technical University of Munich (TUM) have developed a novel model system that can be used to precisely track the growth steps and three-dimensional arrangement of pancreatic cancer cells. It also provides the basis for testing and developing therapeutic approaches. Pancreatic ...

AI identifies cancer cells

“Ikarus lets us identify genes that are potential drivers of cancer”

14-Jun-2022 - How do cancer cells differ from healthy cells? A new machine learning algorithm called “ikarus” knows the answer, reports a team led by MDC bioinformatician Altuna Akalin in the journal Genome Biology. The AI program has found a gene signature characteristic of tumors. When it comes to ...

Researchers engineer cells to destroy malignant tumor cells but leave the rest alone

30-Jun-2021 - Researchers at McMaster University have developed a promising new cancer immunotherapy that uses cancer-killing cells genetically engineered outside the body to find and destroy malignant tumors. The modified "natural killer" cells can differentiate between cancer cells and healthy cells that are ...