Bruker Completes Acquisition of PhenomeX

05-Oct-2023 - Bruker Corporation announced that it has completed the acquisition of PhenomeX, a leading provider of single-cell biology research tools, for $108 million in cash. Bruker announced the agreement to acquire PhenomeX on August 17, 2023. PhenomeX is a functional cell biology company that provides ...

Shaping light lets 2D microscopes capture 4D data

Invention adds new dimension to fluorescent microscopy

20-Feb-2019 - Rice University researchers have added a new dimension to their breakthrough technique that expands the capabilities of standard laboratory microscopes. Two years ago, the Rice lab of chemist Christy Landes introduced super temporal resolution microscopy, a technique that allowed researchers to ...

A new way to stimulate cellular recycling process

18-May-2018 - Brown University researchers studying the biology of aging have demonstrated a new strategy for stimulating autophagy, the process by which cells rebuild themselves by recycling their own worn-out parts. In a study the researchers show that the approach increased the lifespans of worms and flies, ...

Discovery of how HIV hedges its bets opens the door to new therapies

14-May-2018 - A stem cell is one with infinite possibilities. So, for decades, scientists have puzzled over how the cell chooses to keep being a stem cell and continue dividing, or specialize into a specific cell type, like a heart or brain cell. The same type of decision is made by HIV. When the virus infects ...

Genome architecture caught in motion

12-Oct-2017 - Researchers at The Wistar Institute have uncovered new aspects of the three-dimensional organization of the genome, specifically how the genetic material is compacted and de-compacted in a timely fashion during the different phases of the cell cycle. "We are just starting to appreciate that the ...

How does a cell maintain its identity during replication?

18-Sep-2017 - Prior to cell division, chromosomes are seemingly a jumbled mess. During cell division, parent cell chromosomes and their duplicates sort themselves out by condensing, becoming thousands of times more compact than at any other time. Researchers have long assumed that genes become "silent" during ...

How estrogen regulates gene expression

28-Aug-2017 - Estrogen hormones regulate gene expression. They achieve this by first binding to estrogen receptor in the cell nucleus, which triggers the recruitment of different molecules called coactivators in specific order. In a study a team of researchers at Baylor College of Medicine, the University of ...

Allergies? Exhausted regulatory T cells may play a role

28-Aug-2017 - Researchers have evidence that the specialized T cells responsible for maintaining a balanced immune response are vulnerable to exhaustion that disrupts normal functioning and may even contribute to allergic reactions. St. Jude Children's Research Hospital scientists led the study. The report is ...

Synthetic compound linked to hunger-hormone production

31-Jul-2017 - New research suggests that a man-made cousin of a small molecule found in olive oil can disrupt the hunger-signaling pathway. Researchers identified this promising new target by screening a library of roughly 1,600 small molecules for potential disruptors. Because the small molecule could ...

New 3-D imaging reveals how human cell nucleus organizes DNA and chromatin of its genome

31-Jul-2017 - Sixty-four years ago, James Watson and Francis Crick described the now-iconic double helix structure of DNA. A team of researchers at the University of California San Diego School of Medicine and the Salk Institute for Biological Studies describe development and application of new electron ...