Why liver inflammation can damage the kidneys

04-Nov-2024 - The hepatitis E virus actually infects the liver. However, infected liver cells secrete a viral protein that reacts with antibodies in the blood - and as a complex can damage the filtering devices in the kidneys, as researchers at the University of Zurich and University Hospital Zurich have ...

Possible tumour marker found for the development of hepatocellular carcinoma

Cancer cells leave an "imprint" on natural killer cells

19-Mar-2024 - A research team at the MHH is comparing changes in natural killer cells of the innate immune defence system in chronic hepatitis C sufferers as a risk factor for the later development of hepatocellular carcinoma (HCC). Hepatocellular carcinoma (HCC) is a malignant liver tumour that develops from ...

Beethoven’s genome: New study reveals hereditary diseases and a family mystery

Scientists have sequenced the composer’s genome using five genetically matching hair locks

24-Mar-2023 - The study shows Beethoven was predisposed to liver disease, and infected with Hepatitis B, which – combined with his alcohol consumption – may have contributed to his death. Furthermore, DNA from modern relatives points to an extramarital ‘event’ in Beethoven’s paternal line. Johannes Krause, ...

Machine learning diagnoses pneumonia by listening to coughs

A new algorithm could spot early signs of respiratory diseases in hospitals and at home

09-Dec-2022 - Pneumonia is one of the world's leading causes of death and affects over a million people a year in the United States. The disease disproportionately impacts children, older adults, and hospitalized patients. To give them the greatest chance at recovery, it is crucial to catch and treat it early. ...

AI performs as well as medical specialists in analyzing lung disease

02-Aug-2022 - A Nagoya University research group has developed an AI algorithm that accurately and quickly diagnoses idiopathic pulmonary fibrosis, a lung disease. The algorithm makes its diagnosis based only on information from non-invasive examinations, including lung images and medical information collected ...

Hepatitis: 3D structure determination of the ‘gateway’ to the liver

13-May-2022 - Though an essential gateway to the liver, NTCP had not been well described until now. Na+-taurocholate co-transporting polypeptide (NTCP) is a protein located exclusively in the membrane of liver cells that enables recycling of bile acid molecules. It is also the cellular receptor of human ...

A novel painless and reliable allergy test

In vitro mast cells provide unprecedented reliability

23-Mar-2022 - Although allergies are widespread, their diagnosis is complex and, depending on the type of allergy, the prospects of success with therapy are not always clear. Skin tests so far have been unpleasant, time-consuming and associated with a certain risk of triggering an allergic overreaction. ...

Novel hepatitis C virus inhibitory molecules by in vitro evolution

This work could contribute to the development of new biosensors and diagnostic systems for hepatitis C

11-Mar-2022 - An interdisciplinary CSIC team, formed by researchers from the Center for Astrobiology (CAB, CSIC-INTA), the Center for Molecular Biology Severo Ochoa (CBMSO, CSIC-UAM) and the National Center for Biotechnology (CNB, CSIC), has obtained short DNA and structured RNA molecules that inhibit ...

Messengers from gut to brain

Seen for the first time: T cells traveling from the gut and skin to the central nervous system

09-Sep-2021 - Scientists have long been aware of a link between the gut microbiome and the central nervous system (CNS). Until now, however, the immune cells that move from the gut into the CNS and thus the brain had not been identified. A team of researchers in Munich has now succeeded in using violet light ...

A precise measure of protective immunity

New tool aims to make HCV vaccine search easier

23-Feb-2021 - Around 71 million people worldwide are infected with the hepatitis C virus (HCV). One reason why no vaccine against the virus has been found to date is that there are numerous virus variants, some of which differ by more than 30% from each other. Scientists from TWINCORE, the Hannover Medical ...