Next step in light microscopy image improvement

New deep learning architecture enables higher efficiency compared to widely used methods

21-Nov-2024 - It is the computational processing of images that reveals the finest details of a sample placed under all kinds of different light microscopes. Even though this processing has come a long way, there is still room for increasing for example image contrast and resolution. Based on a unique deep ...

A new drug target for psychiatric disorders

11-Sep-2024 - Misha Kudryashev’s lab at the Max Delbrück Center has identified a molecular intermediate of a serotonin receptor that is involved in diseases such as depression and schizophrenia. The study points to a potentially new target for therapeutics. A new study published in “The EMBO Journal” points ...

New technology to study virus infections

"It may be possible to rapidly address emerging pandemics in the future by tailoring our tool to recognize novel viral strains"

26-Jun-2023 - A new tool can identify cells that are actively responding to a SARS-CoV-2 infection. As reported in "Science Advances" by the Gargiulo lab, it can be used to screen for effective COVID-19 therapies and can be tailored to study other viruses as well. When we breathe, the SARS-CoV-2 virus enters ...

Google Maps for tissues

08-Aug-2019 - Modern light microscopic techniques provide extremely detailed insights into organs, but the terabytes of data they produce are usually nearly impossible to process. New software, developed by a team led by MDC scientist Dr. Stephan Preibisch and now presented in Nature Methods, is helping ...

Keeping a cell’s powerhouse in shape

12-Jul-2019 - A German-Swiss team around Professor Oliver Daumke from the MDC has investigated how a protein of the dynamin family deforms the inner mitochondrial membrane. Mitochondria are the powerhouses of our cells, generating energy in the form of chemical compounds such as ATP. To do this job ...