Pathogen identification — next-generation sequencing optimizes diagnostics

Novel method takes inspiration from law enforcement

17-Jun-2024 - Invasive infections such as sepsis require immediate and targeted treatment. Experts from the Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB and group partners have succeeded in establishing a reconceptualized detection principle that can make a crucial contribution to ...

First SARS-CoV-2 genomes in Austria openly available

07-Apr-2020 - The first 21 SARS-CoV-2 genomes in Austria have now been completed and published within the scope of the “Mutational Dynamics of SARS-CoV-2” project recently launched by CeMM in close collaboration with the Medical University of Vienna. The project aims at sequencing 1,000 viral genomes obtained ...

Networks of Gene Activity Control Organ Development

28-Jun-2019 - For the first time, researchers have decoded the genetic programmes that control the development of major organs in humans and other selected mammals – rhesus monkeys, mice, rats, rabbits, and opossums – before and after birth. Using next-generation sequencing technologies, the molecular ...

The secret of brown trout dying uncovered

Searching for clues with next generation technology

30-Nov-2018 - Every summer in Southern Germany, Austria and Switzerland, tons of brown trout perish. An interdisciplinary team from the Technical University of Munich (TUM) has now discovered the culprit of the mysterious dying afflicting brown trout. It is triggered by a previously unknown virus. The setting ...

Agilent Technologies and Agendia Sign Agreement on Molecular Cancer Diagnostics

07-Jun-2017 - Agilent Technologies Inc. and Agendia, Inc. today jointly announced an agreement to expand their relationship to include the development of an RNASeq kit version of Agendia’s currently marketed MammaPrint and BluePrint tests. Agendia’s MammaPrint test provides High-Risk or Low-Risk test results ...

NovogeneAIT Singapore and the Genome Institute of Singapore forge Public-Private Partnership

Establishing whole genome sequencing centre in Singapore

08-Dec-2016 - Novogene, a commercial provider of genomic services and solutions with cutting edge next-generation sequencing and bioinformatics expertise; AITbiotech Pte Ltd, a Singapore biotechnology company; and the Genome Institute of Singapore (GIS) announced today that NovogeneAIT Genomics Singapore ...

Watching RNA fold

02-Nov-2016 - By the time you reach the end of this sentence, RNA folding will have taken place in your body more than 10 quadrillion times. The folding of RNA is essential to life, yet because it happens so rapidly, researchers have difficulty studying the process. "RNA folding during transcription is one of ...

Big data processing enables worldwide bacterial analysis

New bioinformatics tool for searching sequencing data

12-Oct-2016 - Sequencing data from biological samples such as the skin, intestinal tissues, or soil and water are usually archived in public databases. This allows researchers from all over the globe to access them. However, this has led to the creation of extremely large quantities of data. To be able to ...

New, carbon-nanotube tool for ultra-sensitive virus detection and identification

11-Oct-2016 - A new tool that uses a forest-like array of vertically-aligned carbon nanotubes that can be finely tuned to selectively trap viruses by their size can increase the detection threshold for viruses and speed the process of identifying newly-emerging viruses. "Detecting viruses early in an infection ...

Researchers probe secrets of bacterial immune system

05-Oct-2016 - Scientists from New Zealand's University of Otago and the Netherlands are continuing to unlock the secrets of a surprisingly flexible bacterial immune system, called CRISPR-Cas. Just like humans, bacteria are constantly under attack by viruses that try to infect them by injecting viral DNA. This ...