Stem cells - 48 News from the science department for the healthcare industry

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Stem cells - 48 News from the science department for the healthcare industry

Tip: You can further refine your news selection by organizations and countries.

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Markers in iPSC quality control – a new approach to enhance standardization

“Machine learning is an attractive tool to streamline processes”

12-Nov-2024 - Human induced pluripotent stem cells (iPSCs) have a great potential for scientific and medical applications. They are used in research laboratories to model human diseases, helping to uncover underlying mechanisms and developing new therapies. Additionally, they are being tested in clinical ...

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How stem cells and immune cells communicate

Lisec Artz Award for Simon Haas: Groundbreaking discovery of an unknown protective mechanism against blood cancer from stem cells

17-Nov-2023 - Blood cancer is often driven by mutations in stem cells, which are key target cells in the search for innovative early-stage therapies. Dr. Simon Haas, head of a lab within the joint research focus of the Berlin Institute of Health at Charité (BIH), Charité – Universitätsmedizin Berlin, and the ...

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Scientists Find an Unusual Weapon Against Virus

Boosting Weak Immune System

19-Oct-2023 - Infections with cytomegalovirus (CMV) are extremely common and often pose no major threat to the vast majority of people. They can however be deadly for people whose immune system is weakened, e.g., after bone marrow transplantation. Current treatments against CMV infections are very limited and ...

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Building muscle in the lab

This provides a potential for treating patients with muscle diseases – and for those who would like to eat meat, but don’t want to kill animals.

18-Aug-2023 - ETH Zurich Professor Ori Bar-​Nur and his team grow muscle cells in the laboratory. In this case, they are mouse cells, but the researchers are also interested in human and cow cells. Promising applications resonate with both: human muscle tissue cultured in the lab could be used in surgery, ...

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New test to make gene therapy safer

SAGA detects tumour potential of viral vectors for blood stem cells

09-Jul-2021 - When the causes of serious diseases are based on a defective gene, medicine relies on gene therapy. In this strategy, defect-free genes are introduced into the body with the help of certain viruses. In this way, individual forms of congenital blindness, hereditary muscular atrophy or certain ...

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New single-cell analysis of leucemic stem cells

New method to distinguish between cancer stem cells, mature cancer cells and healthy tissue stem cells

23-Mar-2021 - A new method allows stem cells and cancer stem cells to be studied at the single cell level and the resulting cell clones to be traced directly. The method was developed by scientists from the Stem Cell Institute HI-STEM, the German Cancer Research Center (DKFZ), the European Molecular Biology ...

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Induced pluripotent stem cells reveal causes of disease

Using single-cell analyses, researchers systematically searched for correlations between individual genetic variants in induced pluripotent stem cells

08-Mar-2021 - Induced pluripotent stem cells (iPSC) are suitable for discovering the genes that underly complex and also rare genetic diseases. Scientists from the German Cancer Research Center (DKFZ) and the European Molecular Biology Laboratory (EMBL), together with international partners, have studied ...

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Midbrain organoids for automated chemical screening and disease research

Max Planck Innovation licenses process for the generation of organ-like tissue aggregates to biotech company StemoniX

05-Nov-2020 - Sometimes hundreds of thousands of potential therapeutics need to be tested in large-scale, fully automated experiments to identify a single effective drug. Most compounds do not work as desired, and some are even toxic. Since the development of the induced Pluripotent Stem (iPS) Cell technology ...

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New technology provides insight into the development of immune cells

Barcode system enables researchers to follow which development path the cells take at the same time as identifying which genes are actively transcribed as messenger RNAs

14-Aug-2020 - The entire range of our blood and immune cells are derived from hematopoietic stem cells. Yet which genes influence how they develop into the different cell types? Scientists from the German Cancer Research Center (DKFZ) have now developed a new technology to answer this question. A genetic ...

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Epigenetics key to daily production of 10 billion blood cells without mistakes

Study reveals a gene key for blood cell specialisation

10-Aug-2020 - Just one in 2,000 bone marrow cells are hematopoietic stem cells (HSC), but these are the source of the ten billion blood cells humans make every day. In a new study published, researchers from the Centre for Genomic Regulation (CRG), in Barcelona, show that the epigenetic regulator Phf19 is ...

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