Rare side effect discovered in cancer immunotherapy

25-Feb-2025 - Researchers have discovered and analyzed a rare but serious side effect of an innovative form of blood cancer therapy. The results of the study have been published by scientists from Leipzig University Hospital, the Fraunhofer Institute for Cell Therapy and Immunology and Cologne University ...

Immunotherapy against cancer: How therapeutic antibodies do their job

A new super-resolution microscopic method

13-Jan-2025 - A new look at cancer cells: Thanks to an innovative method of super-resolution microscopy, researchers from the University of Würzburg have observed for the first time with molecular resolution in 3D how therapeutic antibodies attack and alter B cells, thereby inducing their destruction. The ...

CRISPR-Cas technology: ETH researchers have uncovered a serious side effect

A molecule designed to make the process more efficient destroys parts of the genome

05-Dec-2024 - Genome editing with various CRISPR-Cas molecule complexes has progressed rapidly in recent years. Hundreds of labs around the world are now working to put these tools to clinical use and are continuously advancing them. CRISPR-Cas tools allow researchers to modify individual building blocks of ...

Sharpening the gene scissors together

Max Delbrück Centre and biotech start-up AlgenScribe cooperate

29-Jul-2024 - The Max Delbrück Center, Berlin, and the biotech company AlgenScribe from Nice have agreed to cooperate to further develop their gene-editing tools. The aim is to utilize synergies, accelerate research, and ultimately develop cell therapies for genetically determined diseases. A special kind of ...

Tumor tissue on a chip: new possibilities for cell therapies and personalized medicine

Therapy effect becomes predictable: Monitoring success individually and in real time

17-May-2024 - How do tumors react to a certain therapeutic approach? Knowing this before the start of a therapy would be of enormous value for people suffering from cancer as well as for the doctors treating them. Researchers at the NMI Natural and Medical Sciences Institute in Reutlingen and the University ...

Computer-engineered DNA to study cell identities

“We can follow with our eyes the color in a petri dish when we give a treatment”

12-Feb-2024 - A new computer program allows scientists to design synthetic DNA segments that indicate, in real time, the state of cells. Reported by the Gargiulo lab in “Nature Communications”, it will be used to screen for anti-cancer or viral infections drugs, or to improve gene and cell-based ...

A protein on cancer cells supports immune response against tumors

Surprising discovery

19-Sep-2023 - Scientists from the German Cancer Research Center (DKFZ) identify a new and surprising function of a membrane protein on the surface of cancer cells: It supports and stabilizes an important "co-stimulatory" factor that enhances the activation of T cells, thus improving the immune response against ...

Evolving viruses to fight bacterial infections

08-Aug-2023 - Multidrug-resistant bacterial infections are one of the most pressing issues in medicine, a situation that is only expected to worsen in the coming decades. The problem is being addressed not only by developing new antibiotics but also by studying antibiotic alternatives, such as phages. Among ...

Waters and Sartorius Expand Collaboration to Deliver Comprehensive Bioanalytics for Downstream Biomanufacturing

06-Jun-2023 - Waters Corporation and Sartorius announced a new collaboration to develop integrated analytical solutions for downstream biomanufacturing, expanding their joint agreement that began with upstream bioprocessing analytics. Software and hardware integrations between the Waters™ PATROL™ ...

AI with infrared imaging enables precise colon cancer diagnostics

Artificial intelligence and infrared imaging automatically classify tumours and are faster than previous methods

16-Feb-2023 - The immense progress in the field of therapy options over the past years has significantly improved the chances of cure for patients with colon cancer. However, these new approaches, such as immunotherapies, require precise diagnosis so that they can be specifically tailored to the individual. ...