Researchers engineer cells to destroy malignant tumor cells but leave the rest alone

30-Jun-2021 - Researchers at McMaster University have developed a promising new cancer immunotherapy that uses cancer-killing cells genetically engineered outside the body to find and destroy malignant tumors. The modified "natural killer" cells can differentiate between cancer cells and healthy cells that are ...

Using oxygen to make cancer visible

20-Feb-2020 - Scientists from the German Cancer Research Center have developed a new method that uses oxygen to identify brain tumors more effectively by magnetic resonance tomography (MRT). To do so, they rely on a metabolic feature of the tumor cells that they can make visible using a completely new imaging ...

Antibodies to a retina protein to be used as a kidney cancer marker

Suggestion of new method for diagnosing kidney cancer

22-Jan-2019 - Sechenov University together with their German colleagues suggest a new highly sensitive, quick, and pain-free method for diagnosing kidney cancer. This method is based on measuring of the immune response to arrestin-1, a retina protein that is synthesized in the cancerous cells of ...

New biomarker links cancer progression to genome instability

High level of specific protein in tumors indicates prognosis

14-Jan-2019 - Our DNA is under constant attack. The delicate molecule that contains our genetic information is extremely vulnerable to everything from environmental agents, such as radiation, to the chemicals in the air we breathe and the food we eat. Genome instability can lead to genetic disorders, chronic ...

Cancer: Tumor transition states

23-Apr-2018 - Researchers at the Université libre de Bruxelles, ULB define for the first time the tumor transition states occurring during cancer progression and identify the tumor cell populations responsible for metastasis. Tumor heterogeneity describes the differences between different cells within a given ...

How a protein promotes cancer progression

14-Dec-2017 - Researchers at Sanford Burnham Prebys Medical Discovery (SBP) and the Technion in Israel have found a new role for the SHARPIN protein. In addition to being one of three proteins in the linear ubiquitin chain assembly complex (LUBAC), regulating NFκB and other inflammatory molecules, SHARPIN ...

Breaking bad: cancer cell drug addiction solved

09-Oct-2017 - Cancer cells can become not only resistant but also addicted to the drugs that serve to kill them. A research team led by professor Daniel Peeper from the Netherlands Cancer Institute has now discovered the underlying mechanism, which may guide the development of more rational alternating ...

Gene-based blood tests identify more skin cancers

03-Apr-2017 - Genetic testing of tumor and blood fluid samples from people with and without one of the most aggressive forms of skin cancer has shown that two new blood tests can reliably detect previously unidentifiable forms of the disease. Researchers at NYU Langone Medical Center and its Perlmutter Cancer ...

QIAGEN joins CANCER-ID consortium for liquid biopsy workflows

Public-private partnership aims to standardize and clinically validate blood-based biomarkers

31-Mar-2017 - QIAGEN N.V. announced it has joined CANCER-ID, a public-private consortium aiming to establish standard protocols and clinical validation for blood-based biomarkers in lung and breast cancer. Rapid advances in the use of liquid biopsies, which enable cancer treatment and monitoring through the ...

Toward glow-in-the-dark tumors

New fluorescent probe could light up cancer

30-Mar-2017 - What if you could plaster cancer cells with glowing "Here We Are" signs, so surgeons could be confident that they'd removed every last speck of a tumor? That's what Haiying Liu has in mind for his new fluorescent probe. "Doctors need to pinpoint cancer tissue, but that can be hard," said Liu, a ...