Thermo Fisher Scientific Announces New Method for Low Level Detection of Volatile Nitrosamines in Tobacco

16-Nov-2011 - USA

Thermo Fisher Scientific Inc. announced a new comprehensive method that uses triple quadrupole GC-MS/MS to achieve lower levels of detection of volatile nitrosamines (VNA) in tobacco. The new method allows environmental laboratories, tobacco companies and government agencies to efficiently separate VNAs while lowering detection limits, increasing specificity and enabling the analysis of many other contaminants in tobacco, including pesticides. The new method is detailed in an application note entitled “Lower Detection Limits of Volatile Nitrosamines in Tobacco by Triple Quadrupole GC-MS/MS,”.

Volatile nitrosamines are a class of compounds that can form in tobacco smoke, as well as during the curing and processing of tobacco. These compounds have been proven to have adverse effects on human health; and two of the VNAs found in tobacco, N-nitrosodiethylamine (NDEA) and N-nitrosodimethylamine (NDMA), are classed as known human carcinogens by regulatory authorities. As a result, these compounds must be thoroughly monitored in order to safeguard human health and comply with increasingly stringent regulations.

The new Thermo Fisher method is a powerful alternative to other traditionally used techniques. By coupling a gas chromatograph to a triple quadrupole mass spectrometer, the new method makes detection limits of 1ng/mL achievable, enabling users to satisfy the increasingly lower detection limits required by governments and regulatory bodies. The method also increases contaminant specificity within a classification and allows many other organic contaminants and chemicals in tobacco to be analyzed simultaneously, including pesticides.

The new method includes GC-MS/MS analysis on the Thermo Scientific TSQ Quantum XLS triple quadrupole GC-MS/MS system using timed selected reaction monitoring (t-SRM). This unique feature enables easy method set-up and allows users to run samples while the instrument automatically determines the optimal time for SRM parameters.

Other news from the department research and development

These products might interest you

Single Quadrupol Massenspektrometer LCMS-2050

Single Quadrupol Massenspektrometer LCMS-2050 by Shimadzu

Compact Single Quadrupole Mass Spectrometry - Expand your analytical possibilities!

Outstanding performance in the smallest space, without compromising speed and sensitivity

iCAP RQ single Quadrupole ICP-MS

iCAP RQ single Quadrupole ICP-MS by Thermo Fisher Scientific

Robust ICP-MS with ease of use and high productivity for routine analysis

A complete multi-element analysis solution for your high-throughput routine laboratory

ICP mass spectrometers
iCAP TQ Triple Quadrupole ICP-MS

iCAP TQ Triple Quadrupole ICP-MS by Thermo Fisher Scientific

Overcome unexpected interferences, reduce detection limits and improve data quality

Ultralow limits of detection with simplicity - even for the most challenging analytical applications

ICP mass spectrometers
ISQ 7610

ISQ 7610 by Thermo Fisher Scientific

Revolutionary GC/MS: Optimized for uninterrupted operation and helium savings

Change columns and sources without interrupting the vacuum and save up to 80 % helium

GC/MS-systems
Loading...

Most read news

More news from our other portals

Under the magnifying glass: The world of microscopy

See the theme worlds for related content

Topic World Spectroscopy

Investigation with spectroscopy gives us unique insights into the composition and structure of materials. From UV-Vis spectroscopy to infrared and Raman spectroscopy to fluorescence and atomic absorption spectroscopy, spectroscopy offers us a wide range of analytical techniques to precisely characterize substances. Immerse yourself in the fascinating world of spectroscopy!

30+ products
5+ whitepaper
30+ brochures
View topic world
Topic World Spectroscopy

Topic World Spectroscopy

Investigation with spectroscopy gives us unique insights into the composition and structure of materials. From UV-Vis spectroscopy to infrared and Raman spectroscopy to fluorescence and atomic absorption spectroscopy, spectroscopy offers us a wide range of analytical techniques to precisely characterize substances. Immerse yourself in the fascinating world of spectroscopy!

30+ products
5+ whitepaper
30+ brochures