NanoHorizons(TM) Awarded Patent Extending MALDI Mass Spectrometer performance

11-Feb-2005

NanoHorizons(TM), Inc., developing applied nanoscale materials and solutions, announced that it has been awarded a patent covering the company's deposited thin-film system for high-throughput small-molecule mass spectrometry. QuickMass(TM)-enhanced targets enable MALDI mass spectrometers to be used for accurate and convenient small molecule analysis using matrix-less and thin-layer matrix test techniques.

"In applications where the mass range limits of MALDI mass spectrometers have forced analytic chemists to use slower and costlier analytic protocols, QuickMass-enhanced targets enable a leap in productivity and capability," said Dr. Stephen Fonash, founder of NanoHorizons.

MALDI is currently the primary mass spectrometry technique for large molecule analysis, operating effectively in the 1,000 to 180,000 amu range. Prior to the advent of QuickMass, small molecule analysis could not be reliably performed using these laser-desorption-based mass spectrometers. Instead, small molecules could only be analyzed using slower and costlier Liquid Chromatography/Ion Electrospray analysis.

QuickMass-enhanced targets utilize NanoHorizons' patented nanoscale non-porous germanium layer to desorb the laser energy of the MALDI instrument, avoiding the use of a matrix and thereby allowing the acquisition of a clear spectrum below 1,000 amu. Using QuickMass+MALDI creates an 80% improvement in the time it takes researchers to get results.

QuickMass-enhanced targets are intended to be used once and discarded or stored for archival purposes or further analysis at a later date. They require no special handling and can be stored "on the shelf" at room temperature indefinitely without degradation. Other notable attempts to enable "matrix-less MALDI" for small molecule analysis have relied on the use of porous silicon -- which has to date resulted in targets that demand complex cleaning, storage, handling and sample preparation procedures and are easily contaminated.

Other news from the department research and development

These products might interest you

IonTamer ToF MS

IonTamer ToF MS by Spacetek Technology

IonTamer instruments are time-of-flight residual gas analysers (TOF-RGA) for the analysis of gases

Compact Time-of-flight residual gas analyzer (TOF-RGA) for process analysis

Residual gas analyzers
PlasmaQuant MS Elite

PlasmaQuant MS Elite by Analytik Jena

LC-ICP-MS Is the Key to the World of Elemental Species

Highest Sensitivity and Lowest Detection Limits with PlasmaQuant MS Series and PQ LC

Xevo TQ Absolute

Xevo TQ Absolute by Waters

A new Tandem Quadrupole Mass Spectrometer for Quantification with Absolute power

Absolute performance, efficiency, productivity, and confidence for your most challenging compounds

mass spectrometers
iCAP RQ single Quadrupole ICP-MS

iCAP RQ single Quadrupole ICP-MS by Thermo Fisher Scientific

Robust ICP-MS with ease of use and high productivity for routine analysis

A complete multi-element analysis solution for your high-throughput routine laboratory

ICP mass spectrometers
iCAP TQ Triple Quadrupole ICP-MS

iCAP TQ Triple Quadrupole ICP-MS by Thermo Fisher Scientific

Overcome unexpected interferences, reduce detection limits and improve data quality

Ultralow limits of detection with simplicity - even for the most challenging analytical applications

ICP mass spectrometers
Thermo Scientific TSQ Triple Quadrupole Mass Spectrometry Systems

Thermo Scientific TSQ Triple Quadrupole Mass Spectrometry Systems by Thermo Fisher Scientific

Confident quantitation with triple quadrupole LC-MS systems

Mass Spectrometry Systems

triple quadrupole mass spectrometers
TSQ 9610 GC-MS/MS

TSQ 9610 GC-MS/MS by Thermo Fisher Scientific

TSQ 9610 GC-MS/MS for superb sensitivity and selectivity with outstanding reliable productivity

Eliminate unnecessary, unplanned instrument downtime, save helium and maximize productivity

triple quadrupole mass spectrometers
Loading...

Most read news

More news from our other portals

Under the magnifying glass: The world of microscopy

See the theme worlds for related content

Topic World Spectroscopy

Investigation with spectroscopy gives us unique insights into the composition and structure of materials. From UV-Vis spectroscopy to infrared and Raman spectroscopy to fluorescence and atomic absorption spectroscopy, spectroscopy offers us a wide range of analytical techniques to precisely characterize substances. Immerse yourself in the fascinating world of spectroscopy!

30+ products
5+ whitepaper
30+ brochures
View topic world
Topic World Spectroscopy

Topic World Spectroscopy

Investigation with spectroscopy gives us unique insights into the composition and structure of materials. From UV-Vis spectroscopy to infrared and Raman spectroscopy to fluorescence and atomic absorption spectroscopy, spectroscopy offers us a wide range of analytical techniques to precisely characterize substances. Immerse yourself in the fascinating world of spectroscopy!

30+ products
5+ whitepaper
30+ brochures

Topic World Mass Spectrometry

Mass spectrometry enables us to detect and identify molecules and reveal their structure. Whether in chemistry, biochemistry or forensics - mass spectrometry opens up unexpected insights into the composition of our world. Immerse yourself in the fascinating world of mass spectrometry!

15+ products
2 whitepaper
15+ brochures
View topic world
Topic World Mass Spectrometry

Topic World Mass Spectrometry

Mass spectrometry enables us to detect and identify molecules and reveal their structure. Whether in chemistry, biochemistry or forensics - mass spectrometry opens up unexpected insights into the composition of our world. Immerse yourself in the fascinating world of mass spectrometry!

15+ products
2 whitepaper
15+ brochures

Topic World Chromatography

Chromatography enables us to separate, identify and thus understand complex substances. Whether in the food industry, pharmaceutical research or environmental analysis - chromatography opens up a treasure trove of information about the composition and quality of our samples. Discover the fascinating world of chromatography!

40+ products
5 whitepaper
35+ brochures
View topic world
Topic World Chromatography

Topic World Chromatography

Chromatography enables us to separate, identify and thus understand complex substances. Whether in the food industry, pharmaceutical research or environmental analysis - chromatography opens up a treasure trove of information about the composition and quality of our samples. Discover the fascinating world of chromatography!

40+ products
5 whitepaper
35+ brochures